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Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter

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Date

2015

Authors

Petersen, Ines
Gabryszewski, Stanislaw J
Johnston, Geoffrey L
Dhingra, Satish K
Ecker, A
Lewis, Rebecca E
De Almeida, Mariana Justino
Straimer, Judith
Henrich, Philipp P.
Palatulan, Eugene

Journal Title

Journal ISSN

Volume Title

Publisher

Blackwell Publishing Ltd

Abstract

The widespread use of chloroquine to treat Plasmodium falciparum infections has resulted in the selection and dissemination of variant haplotypes of the primary resistance determinant PfCRT. These haplotypes have encountered drug pressure and within-host

Description

Keywords

Citation

URI

http://hdl.handle.net/1885/70140

Collections

ANU Research Publications

Source

Molecular Microbiology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1111/mmi.13035

Restricted until

2037-12-31

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01_Petersen_Balancing_drug_resistance_and_2015.pdf (941.56 KB)
02_Petersen_Balancing_drug_resistance_and_2015.pdf (157.01 KB)

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