A Novel Functional Epitope Formed by Domains 1 and 4 of the Human Common beta -Subunit Is Involved in Receptor Activation by Granulocyte Macrophage Colony-stimulating Factor and Interleukin 5*

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dc.contributor.authorMurphy, James
dc.contributor.authorFord, Sally
dc.contributor.authorWiedemann, Ursula
dc.contributor.authorCarr, Paul D
dc.contributor.authorOllis, David
dc.contributor.authorYoung, Ian
dc.date.accessioned2015-12-13T22:28:54Z
dc.date.issued2003
dc.date.updated2015-12-11T08:42:55Z
dc.description.abstractThe receptors for human interleukins 3 and 5 and granulocyte macrophage colony-stimulating factor are composed of ligand-specific α-subunits and a common β-subunit (βc), the major signaling entity. The way in which βc interacts with ligands in the res
dc.identifier.issn0021-9258
dc.identifier.urihttp://hdl.handle.net/1885/74429
dc.publisherAmerican Society for Biochemistry and Molecular Biology Inc
dc.sourceJournal of Biological Chemistry
dc.subjectKeywords: Crystal structure; Interfaces (materials); Mutagenesis; Proliferation; Biochemistry; epitope; fibronectin; granulocyte macrophage colony stimulating factor; interleukin 3; interleukin 5; ligand; protein subunit; epitope; granulocyte macrophage colony stim
dc.titleA Novel Functional Epitope Formed by Domains 1 and 4 of the Human Common beta -Subunit Is Involved in Receptor Activation by Granulocyte Macrophage Colony-stimulating Factor and Interleukin 5*
dc.typeJournal article
local.bibliographicCitation.issue12
local.bibliographicCitation.lastpage10577
local.bibliographicCitation.startpage10572
local.contributor.affiliationMurphy, James, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationFord, Sally, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationWiedemann, Ursula, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationCarr, Paul D, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationOllis, David, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationYoung, Ian, College of Medicine, Biology and Environment, ANU
local.contributor.authoruidMurphy, James, u9914209
local.contributor.authoruidFord, Sally, u8800841
local.contributor.authoruidWiedemann, Ursula, u4161562
local.contributor.authoruidCarr, Paul D, u9206448
local.contributor.authoruidOllis, David, u9200080
local.contributor.authoruidYoung, Ian, u6900649
local.description.embargo2037-12-31
local.description.notesImported from ARIES
local.description.refereedYes
local.identifier.absfor110701 - Allergy
local.identifier.ariespublicationMigratedxPub4119
local.identifier.citationvolume278
local.identifier.doi10.1074/jbc.M211664200
local.identifier.scopusID2-s2.0-0038532303
local.type.statusPublished Version

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