Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage
Date
2005
Authors
Avery, Danielle T
Ellyard, Julia
Mackay, Fabienne
Corcoran, Lynn M
Hodgkin, Phillip D
Tangye, Stuart G
Journal Title
Journal ISSN
Volume Title
Publisher
American Association of Immunologists
Abstract
Plasma cells (PC) or Ig-secreting cells (ISC) are terminally differentiated B cells responsible for the production of protective Ig. ISC can be generated in vitro by culturing human B cells with the T cell-derived stimuli CD40L, IL-2, and IL-10. ISC have
Description
Keywords
Keywords: CD27 antigen; CD38 antigen; CD40 ligand; interleukin 10; interleukin 2; protein Blimp 1; transcription factor; unclassified drug; X box binding protein 1; antigen expression; article; cell division; cell proliferation; controlled study; human; human cell;
Citation
Collections
Source
Journal of Immunology
Type
Journal article
Book Title
Entity type
Access Statement
License Rights
DOI
Restricted until
2037-12-31
Downloads
File
Description