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Increased expression of CD27 on activated human memory B cells correlates with their commitment to the plasma cell lineage

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Date

2005

Authors

Avery, Danielle T
Ellyard, Julia
Mackay, Fabienne
Corcoran, Lynn M
Hodgkin, Phillip D
Tangye, Stuart G

Journal Title

Journal ISSN

Volume Title

Publisher

American Association of Immunologists

Abstract

Plasma cells (PC) or Ig-secreting cells (ISC) are terminally differentiated B cells responsible for the production of protective Ig. ISC can be generated in vitro by culturing human B cells with the T cell-derived stimuli CD40L, IL-2, and IL-10. ISC have

Description

Keywords

Keywords: CD27 antigen; CD38 antigen; CD40 ligand; interleukin 10; interleukin 2; protein Blimp 1; transcription factor; unclassified drug; X box binding protein 1; antigen expression; article; cell division; cell proliferation; controlled study; human; human cell;

Citation

URI

http://hdl.handle.net/1885/49560

Collections

ANU Research Publications

Source

Journal of Immunology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

Restricted until

2037-12-31

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