The roles of eotaxin and the STAT6 signalling pathway in eosinophil recruitment and host resistance tothe nematodes nippostrongylus brasiliensis and heligmosomoides bakeri
Date
2009
Authors
Knott, Michelle L.
Matthaei, Klaus
Foster, Paul S
Dent, Lindsay
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Publisher
Pergamon-Elsevier Ltd
Abstract
Expulsion of adult Nippostrongylus brasiliensis worms from the small intestine is profoundly impaired in signal transducer and activator of transcription (STAT)6-deficient mice. IL-5 transgenic (Tg) mice with constitutive eosinophilia show profound early
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Keywords
Keywords: chemokine; eotaxin; interleukin 13; interleukin 4; interleukin 4 receptor alpha; interleukin 5; STAT6 protein; adaptive immunity; animal experiment; animal model; animal tissue; article; cellular immunity; controlled study; eosinophil; female; gene overex Eotaxin; IL-13; IL-4Ra; Nippostrongylus brasiliensis; Primary and secondary resistance; STAT6
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Source
Molecular Immunology
Type
Journal article
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2037-12-31
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