The roles of eotaxin and the STAT6 signalling pathway in eosinophil recruitment and host resistance tothe nematodes nippostrongylus brasiliensis and heligmosomoides bakeri

Date

2009

Authors

Knott, Michelle L.
Matthaei, Klaus
Foster, Paul S
Dent, Lindsay

Journal Title

Journal ISSN

Volume Title

Publisher

Pergamon-Elsevier Ltd

Abstract

Expulsion of adult Nippostrongylus brasiliensis worms from the small intestine is profoundly impaired in signal transducer and activator of transcription (STAT)6-deficient mice. IL-5 transgenic (Tg) mice with constitutive eosinophilia show profound early

Description

Keywords

Keywords: chemokine; eotaxin; interleukin 13; interleukin 4; interleukin 4 receptor alpha; interleukin 5; STAT6 protein; adaptive immunity; animal experiment; animal model; animal tissue; article; cellular immunity; controlled study; eosinophil; female; gene overex Eotaxin; IL-13; IL-4Ra; Nippostrongylus brasiliensis; Primary and secondary resistance; STAT6

Citation

URI

http://hdl.handle.net/1885/27171

Collections

ANU Research Publications

Source

Molecular Immunology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/j.molimm.2009.05.016

Restricted until

2037-12-31

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Description
01_Knott_The_roles_of_eotaxin_and_the_2009.pdf (2.07 MB)

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