Dissociation from the Oligomeric State Is the Rate-limiting Step in Fibril Formation by K-Casein

Date

2008

Authors

Ecroyd, Heath
Koudelka, Tomas
Thorn, Davic C.
Williams, Danielle M.
Devlin, Glyn
Hoffmann, Peter
Carver, John

Journal Title

Journal ISSN

Volume Title

Publisher

American Society for Biochemistry and Molecular Biology Inc

Abstract

Amyloid fibrils are aggregated and precipitated forms of protein in which the protein exists in highly ordered, long, unbranching threadlike formations that are stable and resistant to degradation by proteases. Fibril formation is an ordered process that

Description

Keywords

Keywords: Agglomeration; Casein; Dissociation; Glycoproteins; High performance liquid chromatography; Mass spectrometry; Nucleation; Self assembled monolayers; Steelmaking; Turbidity; Aggregation mechanisms; Amyloid fibrils; Fibril formations; Fluorescence intensit

Citation

Source

Journal of Biological Chemistry

Type

Journal article

Book Title

Entity type

Access Statement

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Restricted until

2037-12-31