Glutathione transferase Omega 1 is required for the lipopolysaccharide- stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages

Date

2014

Authors

Menon, Deepthi
Coll, Rebecca
O'Neill, Luke A J
Board, Philip

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier BV

Abstract

Bacterial lipopolysaccharide (LPS) stimulation of macrophages and inflammation via the Toll-like receptor 4 (TLR4) signaling pathway through NF-κΒ generates reactive oxygen species (ROS) and proinflammatory cytokines such as IL-1β, IL-6, and TNFα. Bec

Description

Keywords

Citation

Source

Free Radical Biology and Medicine

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31