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Glutathione transferase Omega 1 is required for the lipopolysaccharide- stimulated induction of NADPH oxidase 1 and the production of reactive oxygen species in macrophages

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Authors

Menon, Deepthi
Coll, Rebecca
O'Neill, Luke A J
Board, Philip

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Publisher

Elsevier BV

Abstract

Bacterial lipopolysaccharide (LPS) stimulation of macrophages and inflammation via the Toll-like receptor 4 (TLR4) signaling pathway through NF-κΒ generates reactive oxygen species (ROS) and proinflammatory cytokines such as IL-1β, IL-6, and TNFα. Bec

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Free Radical Biology and Medicine

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Restricted until

2037-12-31