Polymorphism- and Species-Dependent Inactivation of Glutathione Transferase Zeta by Dichloroacetate
Date
Authors
Tzeng, Huey-Fen
Blackburn, Anneke
Board, Philip
Anders, Michael
Journal Title
Journal ISSN
Volume Title
Publisher
American Chemical Society
Abstract
Glutathione transferase zeta catalyzes the glutathione-dependent oxidation or conjugation of a range of α-haloacids. Repeated administration of dichloroacetate to human subjects increases its plasma elimination half- life, and the activity of glutathione
Description
Citation
Collections
Source
Chemical Research in Toxicology
Type
Book Title
Entity type
Access Statement
License Rights
Restricted until
2037-12-31