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Wide genome comparisons reveal the origins of the human X chromosome

Date

2004

Authors

Kohn, Matthias
Kehrer-Sawatzki, Hildegard
Vogel, W
Graves, Jennifer
Hameister, Horst

Journal Title

Journal ISSN

Volume Title

Publisher

Elsevier

Abstract

The eutherian X chromosome has one of the most conserved gene arrangements in mammals. Although earlier comparisons with distantly related mammalian groups pointed towards separate origins for the short and long arms, much deeper comparisons are now possible using draft sequences of the chicken genome, in combination with genome sequences from pufferfish and zebrafish. This enables surprising new insights into the origins of the mammalian X chromosome.

Description

Keywords

Keywords: chromosome analysis; chromosome arm; comparative gene mapping; DNA sequence; gene location; gene rearrangement; gene sequence; genetic conservation; genome analysis; human; human chromosome; human versus animal comparison; mammal; molecular evolution; non

Citation

URI

http://hdl.handle.net/1885/81061

Collections

ANU Research Publications

Source

Trends in Genetics

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/j.tig.2004.09.008

Restricted until

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