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Genetic analysis of four porcine avian influenza viruses isolated from Shandong, China

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Date

2008

Authors

Shi, W.F.
Gibbs, Mark
Zhang, Y.Z.
Zhang, Z.
Zhao, X.M.
Jin, X.
Zhu, C.D.
Yang, M.F.
Yang, N.N.
Cui, Y.J.

Journal Title

Journal ISSN

Volume Title

Publisher

Springer

Abstract

A Bayesian phylogenetic analysis of eight separate gene segments indicated A/Swine/Shandong/2/2003 (H5N1), A/Swine/Shandong/na/2003 (H9N2), A/Swine/Shandong/nb/2003 (H9N2) and A/Swine/Shandong/nc/2005 (H9N2) probably represent two multiple reassortant lineages, that had not been described before, with genes coming from H5N1, H9N2 and other lineages from poultry in Asia. Amino acid motifs within the haemagglutinin sequence of A/Swine/Shandong/nb/2003 suggested it may be able to infect people, whereas the sequences of the other three isolates suggested they would not have had that capability. Our analysis emphasizes the need for a comprehensive study of the interactions between H5N1 and H9N2 viruses in Asia that includes sequencing and phylogenetic investigation.

Description

Keywords

Keywords: animal; animal disease; article; avian influenza; bird; China; classification; genetics; hemagglutination inhibition test; Influenza virus A H9N2; isolation and purification; Orthomyxovirus infection; pathogenicity; swine; virology; virus genome; Animals;

Citation

URI

http://hdl.handle.net/1885/53398

Collections

ANU Research Publications

Source

Archives of Virology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1007/s00705-007-1083-1

Restricted until

2037-12-31

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