Binding of Zn-Chlorin to a synthetic four-helix bundle peptide through histidine ligation

Razeghifard, Mohammad; Wydrzynski, Thomas

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Binding of Zn-Chlorin to a synthetic four-helix bundle peptide through histidine ligation

Date

2003

Authors

Razeghifard, Mohammad

Wydrzynski, Thomas

Publisher

American Chemical Society

Abstract

We have used a two histidine-containing synthetic peptide (Sharp et al. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 10465-10470) as a scaffold to bind Zn(II) chorin e6 (ZnCe6) through histidine ligation. Protocols for the preparation and purification of the