Two modes of β-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3
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Mirza, Shamaruh
Chen, Jinglong
Wen, Bin
Ewans, Cameron
Dai, Jin
Murphy, James M
Young, Ian
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American Society for Biochemistry and Molecular Biology Inc
Abstract
The cytokine interleukin-3 (IL-3) is a critical regulator of inflammation and immune responses in mammals. IL-3 exerts its effects on target cells via receptors comprising an IL-3-specific α-subunit and common β-subunit (βc; shared with IL-5 and granul
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Journal of Biological Chemistry
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2037-12-31
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