β-Nitro-α-amino Acids as Latent α,β-Dehydro-α-amino Acid Residues in Solid-Phase Peptide Synthesis
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Coghlan, Phillip
Easton, Christopher
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ARKAT Foundation
Abstract
β-Nitro-α-amino acids, that are readily accessible through either the reaction of bromoglycine derivatives with alkyl nitronates or the three-component coupling of amines, nitroalkanes and glyoxalate in aqueous base, are easily converted to the correspo
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ARKIVOC