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Expression of rabbit IL-4 by recombinant myxoma viruses enhances virulence and overcomes genetic resistance to myxomatosis

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Date

2004

Authors

Kerr, P J
Perkins, Harvey
Inglis, Barbara
Stagg, Rob
McLaughlin, E
Collins, Susannah
van Leeuwen, Barbara

Journal Title

Journal ISSN

Volume Title

Publisher

Academic Press

Abstract

Rabbit IL-4 was expressed in the virulent standard laboratory strain (SLS) and the attenuated Uriarra (Ur) strain of myxoma virus with the aim of creating a Th2 cytokine environment and inhibiting the development of an antiviral cell-mediated response to

Description

Keywords

Keywords: cytokine; interleukin 4; animal experiment; animal model; article; cellular immunity; coevolution; controlled study; genetic resistance; immunization; Myxoma virus; myxomatosis; nonhuman; pathogenesis; priority journal; protein expression; rabbit; Th2 cel Coevolution; Genetic resistance; IL-4; Myxoma virus; Rabbits

Citation

URI

http://hdl.handle.net/1885/78041

Collections

ANU Research Publications

Source

Virology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

DOI

10.1016/j.virol.2004.02.031

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