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Genetically manipulated mice: a powerful tool with unsuspected caveats

Date

Authors

Matthaei, Klaus

Publisher

Cambridge University Press

Abstract

Although genetic manipulations in mice have provided a powerful tool for investigating gene function in vivo, recent studies have uncovered a number of developmental phenomena that complicate the attribution of phenotype to the specific genetic change. A

Keywords

Keywords: cre recombinase; mifepristone; nerve growth factor receptor; tamoxifen; tetracycline; DNA integration; embryo development; epigenetics; Escherichia coli; gene control; gene deletion; gene expression regulation; gene function; gene overexpression; gene tra

URI

http://hdl.handle.net/1885/29400

Collections

ANU Research Publications

Source

Journal of Physiology

Type

Journal article

DOI

10.1113/jphysiol.2007.134908

Restricted until

2037-12-31

Downloads

File

Description

01_Matthaei_Genetically_manipulated_mice:_2007.pdf (360.92 KB)

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