Genetically manipulated mice: a powerful tool with unsuspected caveats

Date

2007

Authors

Matthaei, Klaus

Journal Title

Journal ISSN

Volume Title

Publisher

Cambridge University Press

Abstract

Although genetic manipulations in mice have provided a powerful tool for investigating gene function in vivo, recent studies have uncovered a number of developmental phenomena that complicate the attribution of phenotype to the specific genetic change. A

Description

Keywords

Keywords: cre recombinase; mifepristone; nerve growth factor receptor; tamoxifen; tetracycline; DNA integration; embryo development; epigenetics; Escherichia coli; gene control; gene deletion; gene expression regulation; gene function; gene overexpression; gene tra

Citation

Source

Journal of Physiology

Type

Journal article

Book Title

Entity type

Access Statement

License Rights

Restricted until

2037-12-31