A recombinant vaccinia virus encoding the interferon-inducible T-cell alpha chemoattractant is attenuated  in vivo

Hamilton, Nicholas H R; Mahalingam, Surendran; Banyer, Joanne; Ramshaw, Ian; Thomson, Scott

A recombinant vaccinia virus encoding the interferon-inducible T-cell alpha chemoattractant is attenuated in vivo

Date

2004

Authors

Hamilton, Nicholas H R

Mahalingam, Surendran

Banyer, Joanne

Ramshaw, Ian

Thomson, Scott

Publisher

Blackwell Publishing Ltd

Abstract

Murine interferon-inducible T-cell alpha chemoattractant (I-TAC) is a potent non-ELR CXC chemokine that predominantly attracts activated T lymphocytes, binds to the receptor CXCR3 and is induced by interferon-γ (IFN-γ). We analysed I-TAC expression by r