The structures of three new Galbulimima alkaloids
Date
2009
Authors
Mander, Lewis
Willis, Anthony
Herlt, Anthony
Taylor, Walter C
Journal Title
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Volume Title
Publisher
Elsevier
Abstract
The structures of three new alkaloids isolated from the bark of the rain forest tree Galbulimima belgraveana, have been determined by a combination of NMR spectroscopy and X-ray crystallography. One of the alkaloids, himgrine (5), was shown to be an oxygenated derivative of himbacine (1), while the second, GB16, (8) proved to be identical with a degradation product from himgaline (4). The remaining alkaloid, GB17 (12) possesses an entirely new and unexpected skeleton.
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Keywords
Keywords: alkaloid; himandrine; himbacine; himgaline; himgrine; unclassified drug; article; bark; degradation; glabulimima belgraveana; Michael addition; nuclear magnetic resonance spectroscopy; oxygenation; skeleton; structure analysis; tree; X ray crystallography Alkaloids; Biosynthesis; Galbulimima belgraveana; Novel structures
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Source
Tetrahedron Letters
Type
Journal article
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Restricted until
2037-12-31
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