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Treatment implications of the altered cytokine-insulin axis in neurodegenerative disease

Date

Authors

Clark, Ian A

Vissel, Bryce

Publisher

Elsevier

Abstract

The disappointments of a series of large anti-amyloid trials have brought home the point that until the driving force behind Alzheimer's disease, and the way it causes harm, are firmly established and accepted, researchers will remain ill-equipped to find

Keywords

Keywords: alpha synuclein; amyloid; apolipoprotein E2; apolipoprotein E3; apolipoprotein E4; bexarotene; calcineurin; cryopyrin; cytokine; DNA methyltransferase 1; insulin; interleukin 1; interleukin 12; interleukin 17; interleukin 23; membrane receptor; monoclonal Alzheimer's disease; DNA hypomethylation; Insulin resistance; Parkinson's disease, a-Synuclein; TNF

URI

http://hdl.handle.net/1885/74904

Collections

ANU Research Publications

Source

Biochemical Pharmacology

Type

Journal article

DOI

10.1016/j.bcp.2013.07.030

Restricted until

2037-12-31

Downloads

File

Description

01_Clark_Treatment_implications_of_the_2013.pdf (881.5 KB)