Formylated phloroglucinols from Eucalyptus loxophleba foliage
Date
2011
Authors
Sidana, Jasmeen
Singh, Sukhvinder
Arora, Sunil Kumar
Foley, William
Singh, Inder Pal
Journal Title
Journal ISSN
Volume Title
Publisher
Elsevier
Abstract
Two new naturally occurring formylated phloroglucinol compounds (FPCs), a dimer, loxophlebal B (10) and a cyclized FPC, loxophlebene (8) together with eight other formylated phloroglucinols (1-7 and 9) were isolated from the chloroform-methanol (8:2) extract of the leaves of Eucalyptus loxophleba ssp. lissophloia. The structures of new compounds were established by comprehensive spectral analysis and by comparison of their NMR data with those of related compounds in the literature. All the isolated compounds were evaluated for anti-leishmanial activity against promastigotes of Leishmania donovani.
Description
Keywords
Keywords: chloroform; dimer; formylated phloroglucinol compound; loxophlebal b; loxophlebene; methanol; phloroglucinol; unclassified drug; antileishmanial activity; article; biological activity; chemical structure; Eucalyptus; Eucalyptus loxophleba; foliage; high p Antileishmanial; Eucalyptus loxophleba; Euglobals; Formylated phloroglucinols; Grandinal; Loxophlebal A
Citation
Collections
Source
Fitoterapia
Type
Journal article
Book Title
Entity type
Access Statement
License Rights
Restricted until
2037-12-31
Downloads
File
Description