The Essential beta-Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis

Rossiter, Amanda E.; Leyton, Denisse; Tveen-Jensen, Karina; Browning, Douglas F.; Sevastsyanovich, Yanina R; Knowles, Timothy J; Nichols, Katie B.; Cunningham, Adam F; Overduin, Michael; Schembri, Mark A.; Henderson, Ian R

The Essential beta-Barrel Assembly Machinery Complex Components BamD and BamA Are Required for Autotransporter Biogenesis

Date

2011

Authors

Rossiter, Amanda E.

Leyton, Denisse

Tveen-Jensen, Karina

Browning, Douglas F.

Sevastsyanovich, Yanina R

Knowles, Timothy J

Nichols, Katie B.

Cunningham, Adam F

Overduin, Michael

Schembri, Mark A.

Publisher

American Society for Microbiology

Abstract

Autotransporter biogenesis is dependent upon BamA, a central component of the β-barrel assembly machinery (BAM) complex. In this report, we detail the role of the other BAM components (BamB-E). We identify the importance of BamD in autotransporter biogenesis and show that BamB, BamC, and BamE are not required.