Safe and effective: anti-tumour necrosis factor therapy use in pregnant patients with Crohn disease and ulcerative colitis
Date
2016-05-11
Authors
Kiely, C J
Subramaniam, K
Platten, J
Pavli, P
Journal Title
Journal ISSN
Volume Title
Publisher
Wiley
Abstract
Biological therapy, particularly the anti-tumour necrosis factor (TNF) antibodies, infliximab and adalimumab, are used for the maintenance of remission for patients with inflammatory bowel diseases (IBD). We present 21 pregnancies in IBD patients exposed to anti-TNF agents between 2007 and 2014. Our study demonstrates that anti-TNF therapy is safe and effective in pregnancy. Rates of foetal complications are similar to IBD cohorts from the pre anti-TNF era.
Description
Keywords
crohn disease, inflammatory bowel disease, pregnancy, tumour necrosis factor-alpha, ulcerative colitis
Citation
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Source
Internal medicine journal
Type
Journal article