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The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum

Martin, Rowena E; Henry, Roselani I; Abbey, Janice; Clements, John D; Kirk, Kiaran


Background The uptake of nutrients, expulsion of metabolic wastes and maintenance of ion homeostasis by the intraerythrocytic malaria parasite is mediated by membrane transport proteins. Proteins of this type are also implicated in the phenomenon of antimalarial drug resistance. However, the initial annotation of the genome of the human malaria parasite Plasmodium falciparum identified only a limited number of transporters, and no channels. In this study we have used a...[Show more]

CollectionsANU Research Publications
Date published: 2005-03-02
Type: Journal article
Source: Genome Biology
DOI: 10.1186/gb-2005-6-3-r26
Access Rights: Open Access


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