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Role of cyclin E in the pathogenesis of hepatocellular carcinoma

Pok, Sharon

Description

Hepatocellular carcinoma (HCC), or primary liver cancer, is the fifth most common cancer worldwide and the third most common cause of cancer mortality (El-Serag 2012). The development of HCC is thought to be a multi-staged process that involves several risk factors including the chronic hepatitis B and C infection, carcinogen exposure, metabolic disease, excessive alcohol consumption and male gender. Accumulation of genetic and epigenetic alterations with DNA-damaged hepatocytes can also...[Show more]

CollectionsOpen Access Theses
Date published: 2013-05-01
Type: Thesis (PhD)
URI: http://hdl.handle.net/1885/9932

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02Whole_Pok.pdfWhole Thesis9.06 MBAdobe PDF    Request a copy


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