Connelly, William; Crunelli, Vincenzo; Errington, Adam
Low-threshold Ca2 spikes (LTS) are an indispensible signaling mechanism for neurons in areas including the cortex, cerebellum, basal ganglia, and thalamus. They have critical physiological roles and have been strongly associated with disorders including epilepsy, Parkinson’s disease, and schizophrenia. However, although dendritic T type Ca2 channels have been implicated in LTS generation, because the properties of low-threshold spiking neuron dendrites are unknown, the precise mechanism has...[Show more]
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