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What assay is optimal for the diagnosis of measles virus infection? An evaluation of the performance of a measles virus real-time reverse transcriptase PCR using the Cepheid SmartCycler? and antigen detection by immunofluorescence

Chua, Kyra Y L; Thapa, Kiran; Yapa, Chaturangi; Somerville, Lucy K; Chen, Sharon C.-A; Dwyer, Dominic E; Sheppeard, V; Kok, Jen


Background: Despite the World Health Organization (WHO)-reported elimination of measles in Australia, importation of cases especially in travellers from Asia continues in Sydney, Australia’s largest city. Laboratory confirmation supports clinico-epidemiological evidence of measles virus infection, and is needed to establish elimination. Objectives: To evaluate the performance of a random access real-time reverse transcriptase polymerase chain reaction (RT-PCR) assay using the moderate...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Journal of Clinical Virology
DOI: 10.1016/j.jcv.2015.07.004


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