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Ion Regulation in the Malaria Parasite

Kirk, Kiaran


Some hours after invading the erythrocytes of its human host, the malaria parasite Plasmodium falciparum induces an increase in the permeability of the erythrocyte membrane to monovalent ions. The resulting net influx of Na+ and net efflux of K+, down their respective concentration gradients, converts the erythrocyte cytosol from an initially high-K+, low-Na+ solution to a high-Na+, low-K+ solution. The intraerythrocytic parasite itself exerts tight control over its internal Na+, K+, Cl-, and...[Show more]

CollectionsANU Research Publications
Date published: 2015
Type: Journal article
Source: Annual Review of Microbiology
DOI: 10.1146/annurev-micro-091014-104506


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