The B subunit of Escherichia coli heat-labile toxin alters the development and antigen-presenting capacity of dendritic cells
Escherichia coli's heat-labile enterotoxin (Etx) and its non-toxic B subunit (EtxB) have been characterized as adjuvants capable of enhancing T cell responses to co-administered antigen. Here, we investigate the direct effect of intravenously administered EtxB on the size of the dendritic and myeloid cell populations in spleen. EtxB treatment appears to enhance the development and turnover of dendritic and myeloid cells from precursors within the spleen. EtxB treatment also gives a dendritic...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Cellular and Molecular Medicine|
|Access Rights:||Open Access|
|01_Griffiths_The_B_subunit_of_Escherichia_2015.pdf||708.93 kB||Adobe PDF|
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