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Developmental gene expression provides clues to relationships between sponge and eumetazoan body plans

Leininger, Sven; Adamski, Marcin; Bergum, Birth; Guder, Corina; Liu, Jing; Laplante, Mary; Brate, Jon; Hoffmann, Friederike; Fortunato, Sofia; Jordal, Signe; Rapp, Hans Tore; Adamska, Maja

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Elucidation of macroevolutionary transitions between diverse animal body plans remains a major challenge in evolutionary biology. We address the sponge-eumetazoan transition by analyzing expression of a broad range of eumetazoan developmental regulatory genes in Sycon ciliatum (Calcispongiae). Here we show that many members of surprisingly numerous Wnt and Tgfi 2 gene families are expressed higher or uniquely in the adult apical end and the larval posterior end. Genes involved in formation of...[Show more]

dc.contributor.authorLeininger, Sven
dc.contributor.authorAdamski, Marcin
dc.contributor.authorBergum, Birth
dc.contributor.authorGuder, Corina
dc.contributor.authorLiu, Jing
dc.contributor.authorLaplante, Mary
dc.contributor.authorBrate, Jon
dc.contributor.authorHoffmann, Friederike
dc.contributor.authorFortunato, Sofia
dc.contributor.authorJordal, Signe
dc.contributor.authorRapp, Hans Tore
dc.contributor.authorAdamska, Maja
dc.date.accessioned2016-02-24T22:40:31Z
dc.identifier.issn2041-1723
dc.identifier.urihttp://hdl.handle.net/1885/98354
dc.description.abstractElucidation of macroevolutionary transitions between diverse animal body plans remains a major challenge in evolutionary biology. We address the sponge-eumetazoan transition by analyzing expression of a broad range of eumetazoan developmental regulatory genes in Sycon ciliatum (Calcispongiae). Here we show that many members of surprisingly numerous Wnt and Tgfi 2 gene families are expressed higher or uniquely in the adult apical end and the larval posterior end. Genes involved in formation of the eumetazoan endomesoderm, such as i 2-catenin, Brachyury and Gata, as well as germline markers Vasa and Pl10, are expressed during formation and maintenance of choanoderm, the feeding epithelium of sponges. Similarity in developmental gene expression between sponges and eumetazoans, especially cnidarians, is consistent with Haeckela €™ s view that body plans of sponges and cnidarians are homologous. These results provide a framework for further studies aimed at deciphering ancestral developmental regulatory networks and their modifications during animal body plans evolution.
dc.publisherMacmillan Publishers Ltd
dc.rightsAuthor/s retain copyright
dc.sourceNature Communications
dc.titleDevelopmental gene expression provides clues to relationships between sponge and eumetazoan body plans
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume5
dc.date.issued2014
local.identifier.absfor060399 - Evolutionary Biology not elsewhere classified
local.identifier.absfor060408 - Genomics
local.identifier.absfor060802 - Animal Cell and Molecular Biology
local.identifier.ariespublicationa383154xPUB2592
local.type.statusPublished Version
local.contributor.affiliationLeininger, Sven, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationAdamski, Marchin, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationBergum, Birth, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationGuder, Corina, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationLiu, Jing, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationLaplante, Mary, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationBrate, Jon, University of Oslo
local.contributor.affiliationHoffmann, Friederike, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationFortunato, Sofia, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationJordal, Signe, Sars International Centre for Marine Molecular Biology
local.contributor.affiliationRapp, Hans Tore, University of Bergen
local.contributor.affiliationAdamska, Maja, College of Medicine, Biology and Environment, ANU
local.bibliographicCitation.issue3905
local.bibliographicCitation.startpage1
local.bibliographicCitation.lastpage15
local.identifier.doi10.1038/ncomms4905
local.identifier.absseo970106 - Expanding Knowledge in the Biological Sciences
dc.date.updated2016-02-24T08:06:22Z
local.identifier.scopusID2-s2.0-84901236288
dcterms.accessRightsOpen Access
CollectionsANU Research Publications

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