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From self sufficiency to dependence: Mechanisms and factors important for autotransporter biogenesis

Leyton, Denisse; Rossiter, Amanda E.; Henderson, Ian R


Autotransporters are a superfamily of proteins that use the type V secretion pathway for their delivery to the surface of Gram-negative bacteria. At first glance, autotransporters look to contain all the functional elements required to promote their own secretion: an amino-terminal signal peptide to mediate translocation across the inner membrane, a central passenger domain that is the secreted functional moiety, and a channel-forming carboxyl terminus that facilitates passenger domain...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Nature Reviews Microbiology
DOI: 10.1038/nrmicro2733


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