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Changes in lipid composition during sexual development of the malaria parasite Plasmodium falciparum

Tran, Phuong N; Brown, Simon H J; Rug, Melanie; Ridgway, Melanie C; Mitchell, Todd W; Maier, Alexander G


Abstract Background The development of differentiated sexual stages (gametocytes) within human red blood cells is essential for the propagation of the malaria parasite, since only mature gametocytes will survive in the mosquito’s midgut. Hence gametocytogenesis is a pre-requisite for transmission of the disease. Physiological changes involved in sexual differentiation are still enigmatic. In particular the lipid metabolism—despite being central...[Show more]

CollectionsANU Research Publications
Date published: 2016-02-06
Type: Journal article
Source: Malaria Journal
DOI: 10.1186/s12936-016-1130-z
Access Rights: Open Access


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