Transmission at the mammalian neuromuscular junction
For more than a century vertebrate nerve-muscle preparations have been extensively investigated. This is not surprising for such preparations are readily accessible and may survive, isolated, in simple solutions for many hours. Furthermore the mechanical response of muscles to direct and indirect stimulation provided some index of activity long before electrical recording techniques were evolved. The concept of the neuromuscular junction as a physiological entity dates from the researches of...[Show more]
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