Comben, Brian Maxwell
Two strains of vaccinia virus were selected
which differed by five separate markers: pock
morphology on the chorioallantoic membrane of the
chick embryo, the production of haemagglutinin,
heat resistance, mouse virulence when inoculated
intracerebrally and type of skin lesion produced
in the rabbit.
homogeneous for the five markers, and that the
markers were stable on pure culture passage.
cultures were infected with mixtures of the two
strains and an analysis was made of the progeny...[Show more]
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