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Recombination between two strains of vaccinia virus

Comben, Brian Maxwell


Two strains of vaccinia virus were selected which differed by five separate markers: pock morphology on the chorioallantoic membrane of the chick embryo, the production of haemagglutinin, heat resistance, mouse virulence when inoculated intracerebrally and type of skin lesion produced in the rabbit. homogeneous for the five markers, and that the markers were stable on pure culture passage. cultures were infected with mixtures of the two strains and an analysis was made of the progeny...[Show more]

CollectionsOpen Access Theses
Date published: 1959-02
Type: Thesis (PhD)


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