Siddle, Hannah V; Deakin, Janine E; Coggill, Penny; Whilming, Laurens; Harrow, Jennifer; Kaufman, Jim; Beck, Stephan; Belov, Katherine
BACKGROUND The major histocompatibility complex (MHC) is a group of genes with a variety of roles in the innate and adaptive immune responses. MHC genes form a genetically linked cluster in eutherian mammals, an organization that is thought to confer functional and evolutionary advantages to the immune system. The tammar wallaby (Macropus eugenii), an Australian marsupial, provides a unique model for understanding MHC gene evolution, as many of its antigen presenting genes are not linked to the...[Show more]
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