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The role of globular heads of the C1q receptor in HPV 16 E2-induced human cervical squamous carcinoma cell apoptosis is associated with p38 MAPK/JNK activation

Gao, Ling-juan; Gu, Ping-qing; Zhao, Wei; Ding, Wen-yan; Zhao, Xue-qing; Guo, Shu-yu; Zhong, Tian-ying


BACKGROUND Human papillomavirus type 16 (HPV 16) E2 protein is a multifunctional DNA-binding protein. HPV 16 E2 regulates many biological responses, including DNA replication, gene expression, and apoptosis. The purpose of this study was to investigate the relationship among the receptor for globular heads of the human C1q (gC1qR) gene expression, HPV 16 E2 transfection and apoptosis regulation in human cervical squamous carcinoma cells (C33a and SiHa). METHODS gC1qR expression was examined in...[Show more]

CollectionsANU Research Publications
Date published: 2013-05-08
Type: Journal article
Source: Journal of Translational Medicine
DOI: 10.1186/1479-5876-11-118


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