Skip navigation
Skip navigation

Functional conservation of the apoptotic machinery from coral to man: the diverse and complex Bcl-2 and caspase repertoires of Acropora millepora

Moya, Aurelie; Sakamaki, Kazuhiro; Mason, Benjamin M; Huisman, Lotte; Forêt, Sylvain; Weiss, Yvonne; Bull, Tara E; Tomii, Kentaro; Imai, Kenichiro; Hayward, David C; Ball, Eldon; Miller, David J

Description

BACKGROUND: Apoptotic cell death is a defining and ubiquitous characteristic of metazoans, but its evolutionary origins are unclear. Although Caenorhabditis and Drosophila played key roles in establishing the molecular bases of apoptosis, it is now clear that cell death pathways of these animals do not reflect ancestral characteristics. Conversely, recent work suggests that the apoptotic networks of cnidarians may be complex and vertebrate-like, hence characterization of the...[Show more]

CollectionsANU Research Publications
Date published: 2016-01-16
Type: Journal article
URI: http://dx.doi.org/10.1186/s12864-015-2355-x
http://hdl.handle.net/1885/95497
Source: BMC Genomics
DOI: 10.1186/s12864-015-2355-x

Download

File Description SizeFormat Image
01_Moya_Functional_Conservation_2016.pdf3.53 MBAdobe PDFThumbnail


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator