LINE-1 Based Insertional Mutagenesis Screens to Identify Genes Involved in Embryonic Stem Cell Differentiation
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Lee, Sung-Hun; Rangasamy, Danny
Description
Background: Knowledge of the intrinsic properties of embryonic stem cells is essential before the possibility of using these cells for therapeutic purposes becomes a reality. Insertional mutagenesis screens are widely used to identify genes sufficient to confer a particular phenotype; however, applications of such approaches are limited to mouse models. Thus, there is a need to develop a new DNA transposon system that allows gene discovery approaches in stem cells. Methods: This study was...[Show more]
Collections | ANU Research Publications |
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Date published: | 2012-03-14 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/95375 |
Source: | Journal of Stem Cell Research & Therapy |
DOI: | 10.4172/2157-7633.1000117 |
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01_Hun Lee_LINE-1_Based_Insertional_2012.pdf | Published Version | 1.68 MB | Adobe PDF |
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