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Aspirin for the prevention of cognitive decline in the elderly: rationale and design of a neuro-vascular imaging study (ENVIS-ion)

Reid, Christopher M; Storey, Elsdon; Wong, Tien Y.; Woods, Robyn; Tonkin, Andrew; Wang, Jie; Kam, Anthony; Janke, Andrew; Essex, Rowan; Abhayaratna, Walter; Budge, Marc


BACKGROUND This paper describes the rationale and design of the ENVIS-ion Study, which aims to determine whether low-dose aspirin reduces the development of white matter hyper-intense (WMH) lesions and silent brain infarction (SBI). Additional aims include determining whether a) changes in retinal vascular imaging (RVI) parameters parallel changes in brain magnetic resonance imaging (MRI); b) changes in RVI parameters are observed with aspirin therapy; c) baseline cognitive function correlates...[Show more]

CollectionsANU Research Publications
Date published: 2012-02-08
Type: Journal article
Source: BMC Neurology
DOI: 10.1186/1471-2377-12-3


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