Simultaneous alignment of short reads against multiple genomes
Genome resequencing with short reads generally relies on alignments against a single reference. GenomeMapper supports simultaneous mapping of short reads against multiple genomes by integrating related genomes (e.g., individuals of the same species) into a single graph structure. It constitutes the first approach for handling multiple references and introduces representations for alignments against complex structures. Demonstrated benefits include access to polymorphisms that cannot be...[Show more]
|Collections||ANU Research Publications|
|01_Schneeberger_Simultaneous_alignment_of_2009.pdf||Published Version||196.64 kB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.