Characteristics of Australian cohort study participants who do and do not take up an additional invitation to join a long-term biobank: The 45 and Up Study
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Banks, Emily; Herbert, Nicol; Mather, Tanya; Rogers, Kris; Jorm, Louisa
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BACKGROUND Large-scale population biobanks are critical for future research integrating epidemiology, genetic, biomarker and other factors. Little is known about the factors influencing participation in biobanks. This study compares the characteristics of biobank participants with those of non-participants, among members of an existing cohort study. METHODS Individuals aged 45 and over participating in The 45 and Up Study and living ≤20km from central Wagga Wagga, New South Wales (NSW),...[Show more]
dc.contributor.author | Banks, Emily | |
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dc.contributor.author | Herbert, Nicol | |
dc.contributor.author | Mather, Tanya | |
dc.contributor.author | Rogers, Kris | |
dc.contributor.author | Jorm, Louisa | |
dc.date.accessioned | 2016-01-11T04:10:51Z | |
dc.date.available | 2016-01-11T04:10:51Z | |
dc.identifier.issn | 1756-0500 | |
dc.identifier.uri | http://hdl.handle.net/1885/95307 | |
dc.description.abstract | BACKGROUND Large-scale population biobanks are critical for future research integrating epidemiology, genetic, biomarker and other factors. Little is known about the factors influencing participation in biobanks. This study compares the characteristics of biobank participants with those of non-participants, among members of an existing cohort study. METHODS Individuals aged 45 and over participating in The 45 and Up Study and living ≤20km from central Wagga Wagga, New South Wales (NSW), Australia (rural/regional area) or ≤10km from central Parramatta, NSW (urban area) (n=2340) were invited to join a biobank, giving a blood sample and having additional measures taken, including height, weight, waist circumference, heart rate and blood pressure. RESULTS The overall uptake of the invitation to participate was 33% (762/2340). The response rate was 41% (410/1002) among participants resident in the regional area, and 26% (352/1338) among those resident in the urban area. Characteristics associated with significantly decreased participation were being aged 80 and over versus being aged 45-64 (participation rate ratio: RR = 0.45, 95%CI 0.34-0.60), not being born in Australia versus being born in Australia (0.69, 0.59-0.81), having versus not having a major disability (0.54, 0.38-0.76), having full-time caregiving responsibilities versus not being a full-time carer (0.62, 0.42-0.93) and being a current smoker versus never having smoked (0.66, 0.50-0.89). Factors associated with increased participation were being in part-time work versus not being in paid work (1.24, 1.07-1.44) and having an annual household income of ≥$50,000 versus <$20,000 (1.50, 1.26-1.80). CONCLUSIONS A range of socio-economic, health and lifestyle factors are associated with biobank participation among members of an existing cohort study, with factors relating to health-seeking behaviours and access difficulties or time limitations being particularly important. If more widespread participation in biobanking is desired, particularly to ensure sufficient numbers among those most affected by these issues, specific efforts may be required to increase participation in certain groups such as migrants, the elderly, and those in poor health. Whilst caution should be exercised when generalising estimates of absolute prevalence from biobanks, estimates for many internal comparisons are likely to remain valid. | |
dc.description.sponsorship | This specific project was funded by The Cancer Council NSW. Emily Banks is supported by the National Health and Medical Research Council. | |
dc.publisher | BioMed Central | |
dc.rights | © Banks et al.; licensee BioMed Central Ltd. 2012 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |
dc.source | BMC Research Notes | |
dc.subject | aged | |
dc.subject | aged, 80 and over | |
dc.subject | blood pressure | |
dc.subject | body height | |
dc.subject | body weight | |
dc.subject | cohort studies | |
dc.subject | female | |
dc.subject | health status | |
dc.subject | heart rate | |
dc.subject | humans | |
dc.subject | life style | |
dc.subject | likelihood functions | |
dc.subject | linear models | |
dc.subject | male | |
dc.subject | middle aged | |
dc.subject | new south wales | |
dc.subject | phlebotomy | |
dc.subject | questionnaires | |
dc.subject | research subjects | |
dc.subject | socioeconomic factors | |
dc.subject | tissue donors | |
dc.subject | waist circumference | |
dc.subject | biological specimen banks | |
dc.subject | health behavior | |
dc.subject | health knowledge, attitudes, practice | |
dc.title | Characteristics of Australian cohort study participants who do and do not take up an additional invitation to join a long-term biobank: The 45 and Up Study | |
dc.type | Journal article | |
local.description.notes | Imported from ARIES | |
local.identifier.citationvolume | 5 | |
dc.date.issued | 2012-11-27 | |
local.identifier.absfor | 119900 | |
local.identifier.ariespublication | f5625xPUB2215 | |
local.publisher.url | http://www.biomedcentral.com/ | |
local.type.status | Published Version | |
local.contributor.affiliation | Banks, Emily, College of Medicine, Biology and Environment, CMBE Research School of Population Health, Natl Centre for Epidemiology & Population Health, The Australian National University | |
local.contributor.affiliation | Herbert, Nicol, The Sax Institute, Australia | |
local.contributor.affiliation | Muller (previously Mather), Tanya, College of Medicine, Biology and Environment, CMBE Research School of Population Health, Natl Centre for Epidemiology & Population Health, The Australian National University | |
local.contributor.affiliation | Rogers, Kris, The Sax Institute, Australia | |
local.contributor.affiliation | Jorm, Louisa , The Sax Institute , Australia | |
local.identifier.essn | 1756-0500 | |
local.bibliographicCitation.issue | 1 | |
local.bibliographicCitation.startpage | 655 | |
local.bibliographicCitation.lastpage | 6 | |
local.identifier.doi | 10.1186/1756-0500-5-655 | |
local.identifier.absseo | 929999 | |
dc.date.updated | 2016-02-24T08:55:49Z | |
local.identifier.scopusID | 2-s2.0-84869880549 | |
Collections | ANU Research Publications |
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