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Coevolution of amino acid residues in the key photosynthetic enzyme Rubisco

Wang, Mingcong; Kapralov, Maxim V.; Anisimova, Maria


BACKGROUND One of the key forces shaping proteins is coevolution of amino acid residues. Knowing which residues coevolve in a particular protein may facilitate our understanding of protein evolution, structure and function, and help to identify substitutions that may lead to desired changes in enzyme kinetics. Rubisco, the most abundant enzyme in biosphere, plays an essential role in the process of carbon fixation through photosynthesis, thus facilitating life on Earth. This makes Rubisco an...[Show more]

CollectionsANU Research Publications
Date published: 2011-09-23
Type: Journal article
Source: BMC Evolutionary Biology
DOI: 10.1186/1471-2148-11-266


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