Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases?
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Hadler, Kieran S; Cassady, A Ian; Weber, Jane; Robinson, Jodie; Burrows, Allan; Kelly, Gregory; Guddat, Luke W.; Hume, David A.; Schenk, Gerhard; Flanagan, Jack U.; Huber, Thomas
Description
BACKGROUND Tartrate-resistant acid phosphatases (TRAcPs), also known as purple acid phosphatases (PAPs), are a family of binuclear metallohydrolases that have been identified in plants, animals and fungi. The human enzyme is a major histochemical marker for the diagnosis of bone-related diseases. TRAcPs can occur as a small form possessing only the ~35 kDa catalytic domain, or a larger ~55 kDa form possessing both a catalytic domain and an additional N-terminal domain of unknown function. Due...[Show more]
Collections | ANU Research Publications |
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Date published: | 2008-02-26 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/95298 |
Source: | BMC Research Notes |
DOI: | 10.1186/1756-0500-1-78 |
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01_Hadler_Identification_of_a_non-purple_2008.pdf | Published Version | 1.11 MB | Adobe PDF |
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