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Resampling procedures to identify important SNPs using a consensus approach

Pardy, Christopher; Motyer, Allan; Wilson, Susan

Description

Our goal is to identify common single-nucleotide polymorphisms (SNPs) (minor allele frequency > 1%) that add predictive accuracy above that gained by knowledge of easily measured clinical variables. We take an algorithmic approach to predict each phenotypic variable using a combination of phenotypic and genotypic predictors. We perform our procedure on the first simulated replicate and then validate against the others. Our procedure performs well when predicting Q1 but is less successful for...[Show more]

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/95284
Source: BMC Proceedings
DOI: 10.1186/1753-6561-5-S9-S59

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