Thrombolysis ImPlementation in Stroke (TIPS): evaluating the effectiveness of a strategy to increase the adoption of best evidence practice – protocol for a cluster randomised controlled trial in acute stroke care
Paul, Christine L.; Levi, Christopher R.; D'Este, Catherine; Parsons, Mark W.; Bladin, Christopher F.; Lindley, Richard; Attia, John R.; Henskens, Frans; Lalor, Erin; Longworth, Mark; Middleton, Sandy; Ryan, Annika; Kerr, Erin; Sanson-Fisher, Robert W.
BACKGROUND Stroke is a leading cause of death and disability internationally. One of the three effective interventions in the acute phase of stroke care is thrombolytic therapy with tissue plasminogen activator (tPA), if given within 4.5 hours of onset to appropriate cases of ischaemic stroke. OBJECTIVES To test the effectiveness of a multi-component multidisciplinary collaborative approach compared to usual care as a strategy for increasing thrombolysis rates for all stroke patients at...[Show more]
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