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Defining the chromatin signature of inducible genes in T cells

Lim, Pek S; Hardy, Kristine; Bunting, Karen; Ma, Lina; Peng, Kaiman; Chen, Xinxin; Shannon, Mary F


BACKGROUND Specific chromatin characteristics, especially the modification status of the core histone proteins, are associated with active and inactive genes. There is growing evidence that genes that respond to environmental or developmental signals may possess distinct chromatin marks. Using a T cell model and both genome-wide and gene-focused approaches, we examined the chromatin characteristics of genes that respond to T cell activation. RESULTS To facilitate comparison of genes with...[Show more]

CollectionsANU Research Publications
Date published: 2009-10-06
Type: Journal article
Source: Genome Biology
DOI: 10.1186/gb-2009-10-10-r107


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