Duplicability of self-interacting human genes
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Perez-Bercoff, Asa; Makino, Takashi; McLysaght, Aoife
Description
BACKGROUND There is increasing interest in the evolution of protein-protein interactions because this should ultimately be informative of the patterns of evolution of new protein functions within the cell. One model proposes that the evolution of new protein-protein interactions and protein complexes proceeds through the duplication of self-interacting genes. This model is supported by data from yeast. We examined the relationship between gene duplication and self-interaction in the human...[Show more]
Collections | ANU Research Publications |
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Date published: | 2010-05-28 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/95184 |
Source: | BMC Evolutionary Biology |
DOI: | 10.1186/1471-2148-10-160 |
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01_Perez-Bercoff_Duplicability_of_2010.pdf | Published Version | 685.92 kB | Adobe PDF |
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