Plasticity of DNA methylation in mouse T cell activation and differentiation
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Li, Yan; Chen, Guobing; Ma, Lina; Ohms, Stephen J; Sun, Chao; Shannon, M Frances; Fan, Jun Y
Description
BACKGROUND Circulating CD4+ T helper cells are activated through interactions with antigen presenting cells and undergo differentiation into specific T helper cell subsets depending on the type of antigen encountered. In addition, the relative composition of the circulating CD4+ T cell population changes as animals mature with an increased percentage of the population being memory/effector type cells. RESULTS Here, we report on the highly plastic nature of DNA methylation at the genome-wide...[Show more]
Collections | ANU Research Publications |
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Date published: | 2012-05-29 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/95177 |
Source: | BMC Molecular Biology |
DOI: | 10.1186/1471-2199-13-16 |
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01_Li_Plasticity_of_DNA_methylation_2012.pdf | Published Version | 1.34 MB | Adobe PDF |
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