Li, Yan; Chen, Guobing; Ma, Lina; Ohms, Stephen J; Sun, Chao; Shannon, M Frances; Fan, Jun Y
BACKGROUND Circulating CD4+ T helper cells are activated through interactions with antigen presenting cells and undergo differentiation into specific T helper cell subsets depending on the type of antigen encountered. In addition, the relative composition of the circulating CD4+ T cell population changes as animals mature with an increased percentage of the population being memory/effector type cells. RESULTS Here, we report on the highly plastic nature of DNA methylation at the genome-wide...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.