670-nm light treatment reduces complement propagation following retinal degeneration
AIM Complement activation is associated with the pathogenesis of age-related macular degeneration (AMD). We aimed to investigate whether 670-nm light treatment reduces the propagation of complement in a light-induced model of atrophic AMD. METHODS Sprague-Dawley (SD) rats were pretreated with 9 J/cm(2) 670-nm light for 3 minutes daily over 5 days; other animals were sham treated. Animals were exposed to white light (1,000 lux) for 24 h, after which animals were kept in dim light (5 lux) for 7...[Show more]
|Collections||ANU Research Publications|
|Source:||Journal of Neuroinflammation|
|01_Rutar_670-nm_light_treatment_reduces_2012.pdf||Published Version||1.59 MB||Adobe PDF|
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