Further exploration of the heterocyclic diversity accessible from the allylation chemistry of indigo
Diversity-directed synthesis based on the cascade allylation chemistry of indigo, with its embedded 2,2'-diindolic core, has resulted in rapid access to new examples of the hydroxy-8a,13-dihydroazepino[1,2-a:3,4-b']diindol-14(8H)-one skeleton in up to 51% yield. Additionally a derivative of the novel bridged heterocycle 7,8-dihydro-6H-6,8a-epoxyazepino[1,2-a:3,4-b']diindol-14(13H)-one was produced when the olefin of the allylic substrate was terminally disubstituted. Further optimisation also...[Show more]
|Collections||ANU Research Publications|
|Source:||Beilstein Journal of Organic Chemistry|
|01_Shakoori_Further_exploration_of_the_2015.pdf||Published Version||3.23 MB||Adobe PDF|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.