Prichard, Zoe; Jorm, Anthony F; Prior, M H; Sanson, Ann Veronica; Smart, Diana; Zhang, Yi; Huttley, Gavin Austin; Easteal, Simon
Anxiety problems and associated temperamental traits are multifactorial, determined by the interaction of genetic and environmental factors. Genetic effects may involve both neurotransmitters and hormones. A good candidate gene for association with anxiety-related traits is the estrogen receptor (ESRα). Estrogen exerts an effect on mood and behavior in humans through gene regulation on binding to estrogen receptor protein. Association between ESRα polymorphism and anxiety-related traits was...[Show more]
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