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Association of polymorphisms of the estrogen receptor gene with anxiety-related traits in children and adolescents: A longitudinal study

Prichard, Zoe; Jorm, Anthony F; Prior, M H; Sanson, Ann Veronica; Smart, Diana; Zhang, Yi; Huttley, Gavin Austin; Easteal, Simon


Anxiety problems and associated temperamental traits are multifactorial, determined by the interaction of genetic and environmental factors. Genetic effects may involve both neurotransmitters and hormones. A good candidate gene for association with anxiety-related traits is the estrogen receptor (ESRα). Estrogen exerts an effect on mood and behavior in humans through gene regulation on binding to estrogen receptor protein. Association between ESRα polymorphism and anxiety-related traits was...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
Source: American Journal of Medical Genetics, Part A
DOI: 10.1002/ajmg.10181


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