Skip navigation
Skip navigation

Successful boosting of a DNA measles immunization with an oral plant-derived measles virus vaccine

Webster, Diane; Cooney, Michelle; Huang, Zhongjun; Drew, Damian; Ramshaw, Ian; Dry, Ian B; Strugnell, R; Martin, Jenny; Wendler, E

Description

Despite eradication attempts, measles remains a global health concern. Here we report results that demonstrate that a single-dose DNA immunization followed by multiple boosters, delivered orally as a plant-derived vaccine, can induce significantly greater quantities of measles virus-neutralizing antibodies than immunization with either DNA or plant-derived vaccines alone. This represents the first demonstration of an enhanced immune response to a prime-boost vaccination strategy combining a DNA...[Show more]

CollectionsANU Research Publications
Date published: 2002
Type: Journal article
URI: http://hdl.handle.net/1885/94634
Source: Journal of Virology
DOI: 10.1128/JVI.76.15.7910-7912.2002

Download

File Description SizeFormat Image
01_Webster_Successful_boosting_of_a_DNA_2002.pdf68.63 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator